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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 88 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Integrin β5 Rabbit Polyclonal Antibody detects endogenous levels of Integrin β5 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Integrin β5 also known as ITGB5 is a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrin β5 plays a crucial role in cell adhesion and signaling, functioning as a receptor that mediates interactions between cells and the extracellular matrix. Integrin β5 is primarily located on the cell surface, where anti-Integrin β5 antibody (B-10) can detect heterodimers formed with various α subunits, allowing binding to ligands such as fibronectin and vitronectin. Proper localization of Integrin β5 is essential for function, as Integrin β5 facilitates signal transmission from the extracellular environment to the cell interior, influencing processes such as cell migration, proliferation, and survival. Through engagement with the extracellular matrix, Integrin β5 supports structural integrity and activates intracellular signaling pathways vital for cellular responses to external stimuli. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7, Jurkat cells, using Integrin β5 Rabbit Polyclonal Antibody (EAB11787) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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