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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 47 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ING1 Rabbit Polyclonal Antibody detects endogenous levels of ING1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ING1 (Inhibitor of growth protein 1) is a tumor suppressor protein that can induce cell growth arrest and apoptosis. ING1 protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. ING1 plays a significant role in regulating cell growth by cooperating with tumor suppressor p53/TP53, thereby modulating p53-dependent transcriptional activation, which is vital for maintaining cellular homeostasis and preventing uncontrolled cell proliferation. ING1 is primarily located in the nucleus, where ING1 exerts its functions, and exists in several isoforms, including p47ING1, p33ING1, and p24ING1, each with distinct expression patterns across various tissues. |
| Product Image Gallery | |
 Western blot analysis of extracts on U2OS cells, using ING1 Rabbit Polyclonal Antibody (EAB11783) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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