www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 84 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Mitofilin Rabbit Polyclonal Antibody detects endogenous levels of Mitofilin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Mitofilin also known as IMMT, HMP, PIG4, P87/89 is a crucial 758 amino acid inner mitochondrial membrane protein that plays a significant role in maintaining mitochondrial cristae morphology, which is vital for efficient cellular respiration. Mitofilin exists in three alternatively spliced isoforms, each contributing to the formation and organization of cristae junctions and normal tubular cristae, which are essential for efficient cellular respiration. The structural integrity of the cristae is critical, as Mitofilin provides a large surface area for the electron transport chain and ATP synthesis, thereby influencing overall mitochondrial function and energy production. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse heart cells, using Mitofilin Rabbit Polyclonal Antibody (EAB11795) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
