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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 82 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MCM5 Rabbit Polyclonal Antibody detects endogenous levels of MCM5 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MCM5 also known as Cdc46 is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. MCM5 plays a crucial role in DNA replication as a member of the mini-chromosome maintenance (MCM) protein family, which is essential for ensuring that DNA replication occurs only once per cell cycle. This regulation is vital for maintaining genomic stability, as improper replication can lead to mutations and cancer. MCM5, along with other MCM proteins, is involved in the formation of the MCM2-7 complex, which acts as a helicase to unwind DNA during replication. MCM5 is particularly important during the transition from the G1 to S phase of the cell cycle, where expression peaks, indicating an active role in preparing the cell for DNA synthesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, Jurkat, NIH/3T3 cells, using MCM5 Rabbit Polyclonal Antibody (EAB11799) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue, using MCM5 Rabbit Polyclonal Antibody (EAB11799) at 1:100 dilution.
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