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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 95 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Matrin 3 Rabbit Polyclonal Antibody detects endogenous levels of Matrin 3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Matrin 3 also known as MATR3 is a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Matrin 3 contains one matrin-type zinc finger and two RNA recognition motif (RRM) domains, which are essential for RNA processing and gene expression regulation. Located primarily in the nucleus, matrin 3 is involved in the formation of the internal fibrogranular network, which provides structural support for nuclear architecture. matrin 3 is particularly important for nuclear retention of defective RNAs, as matrin 3 interacts with the PSF-p54/NRB heteromer complex, thereby preventing the accumulation of faulty transcripts that could lead to cellular dysfunction. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse brain cells, using Matrin 3 Rabbit Polyclonal Antibody (EAB11797) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 95 kDa; Observed band size: 95-130 kDa |
