www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2a | Monoclonal | WB, IP, IHC-P, IF/ICC, FC, ELISA | 166 | Human, Mouse, Rat, Pig |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IP=1:100-500 IHC-P=1:1000-5000 IF/ICC=1:100-500 FC=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MRC1/CD206 Mouse Monoclonal Antibody detects endogenous levels of MRC1/CD206 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CD206 also known as MMR, MRC1 is a type I transmembrane receptor protein predominantly expressed on the surface of macrophages, immature dendritic cells, hepatic and lymphatic endothelial cells, retinal pigment epithelium (RPE), and mesangial cells. This cell surface localization enables CD206 to function as a phagocytic and endocytic receptor, recognizing carbohydrate ligands on the surfaces of pathogens and facilitating their uptake and clearance by the immune system. The extracellular portion of CD206 includes eight C-type carbohydrate recognition domains (CRDs) clustered together to achieve high-affinity binding to saccharides like mannose, fucose, and N-acetylglucosamine present on bacteria, fungi, and viruses. |
| Product Image Gallery | |
 Western blot analysis of extracts on Human liver, Human placenta cells, using MRC1/CD206 Mouse Monoclonal Antibody (EAB22137) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue, using MRC1/CD206 Mouse Monoclonal Antibody (EAB22137) at 1:2000 dilution.
|
