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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 35 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Nek7 Rabbit Polyclonal Antibody detects endogenous levels of Nek7 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Nek7(NIMA related kinase 7) plays a crucial role in regulating mitosis, particularly during the G2 to M phase transition, where Nek7 is essential for proper cell division. This regulation is vital for maintaining genomic stability and preventing the onset of diseases such as cancer, as aberrations in mitotic processes can lead to aneuploidy and tumorigenesis. Nek7 is primarily localized in the cytoplasm and is highly expressed in various tissues, including lung, testis, muscle, spleen, heart, liver, leukocytes, and brain, while showing lower expression levels in the ovary, prostate, and kidney, and absent in the small intestine. Nek7′s cellular localization is important for coordinating cell division, which is essential for maintaining proper cellular function and preventing diseases such as cancer. |
| Product Image Gallery | |
 Western blot analysis of extracts on COLO205, Jurkat, HepG2 cells, using Nek7 Rabbit Polyclonal Antibody (EAB11802) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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