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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 108 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ORP1 Rabbit Polyclonal Antibody detects endogenous levels of ORP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ORP1 also known as OSBPL1A is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. ORP1 plays a crucial role in lipid metabolism and cellular signaling, particularly in lipid transport within cells. ORP1 is primarily located in the endoplasmic reticulum and can translocate to the Golgi apparatus in response to oxysterol binding, which is vital for maintaining cellular lipid homeostasis and facilitating vesicle transport. ORP1 features a highly conserved OSBP-type sterol-binding region and a pleckstrin homology domain, allowing interactions with various lipids, including phosphatidic acid and phosphatidylinositol 3-phosphate. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431 cells, using ORP1 Rabbit Polyclonal Antibody (EAB14928) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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