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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 59 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PPM1G Rabbit Polyclonal Antibody detects endogenous levels of PPM1G protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PPM1G also known as PP2Cγ, PP2CG is a member of the PP2C family of Ser/Thr protein phosphatases. PPM1G plays a crucial role in cellular signaling by acting as a serine/threonine protein phosphatase, which is essential for the regulation of various cellular processes, including cell division, apoptosis, and stress responses. PPM1G is primarily located in the cytoplasm and is widely expressed, with particularly high levels found in the testis, skeletal muscle, and heart. PPM1G localization allows for the timely regulation of dephosphorylation events that are critical for the function of pre-mRNA splicing factors, thereby facilitating the formation of the functional spliceosome. PPM1G modulation of these processes underscores its importance in maintaining cellular homeostasis and responding to stress, making PPM1G a vital target for research in cell biology and disease mechanisms. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using PPM1G Rabbit Polyclonal Antibody (EAB11831) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry of paraffin-embedded Human tonsil tissue, using PPM1G Rabbit Polyclonal Antibody (EAB11831) at 1:100 dilution.
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