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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 64 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RanGAP1 Rabbit Polyclonal Antibody detects endogenous levels of RanGAP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RanGAP1 is a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. RanGAP1 plays a crucial role in regulating the transport of proteins and RNA across the nuclear envelope, which is essential for maintaining cellular function and homeostasis. Located predominantly in the nucleus, RanGAP1 is involved in the hydrolysis of GTP to GDP, thereby controlling the active and inactive states of the RanGTPase. This regulation is vital for processes such as DNA replication and mitosis, as well as the transport of macromolecules through the nuclear pore complex. The interplay between Ran GAP1 and RCC1, which promotes the exchange of GDP for GTP, highlights the importance of RanGAP1 in cellular signaling pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using RanGAP1 Rabbit Polyclonal Antibody (EAB14946) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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