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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 24 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rab8A Rabbit Polyclonal Antibody detects endogenous levels of Rab8A protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rab8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. Rab8A plays a crucial role in intracellular transport, particularly in vesicle movement between the endoplasmic reticulum and Golgi apparatus, which is essential for proper protein secretion. Rab8A protein localizes primarily in the cytoplasm and regulates vesicle trafficking, ensuring proteins reach correct destinations within cells. Rab8A′s importance in maintaining cellular function stems from involvement in both endocytosis and exocytosis processes, vital for nutrient uptake and waste removal. Rab8A interacts with various effector proteins that facilitate docking and fusion of transport vesicles with target membranes, highlighting an integral role in cellular transport machinery. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using Rab8A Rabbit Polyclonal Antibody (EAB14948) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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