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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P | 32 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:100-500 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | StAR Rabbit Monoclonal Antibody detects endogenous levels of StAR protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
StAR plays a crucial role in steroid hormone synthesis by facilitating cholesterol transport into mitochondria, where conversion to pregnenolone occurs as the precursor for all steroid hormones. This transport represents the first and rate-limiting step in steroidogenesis, making StAR essential for producing hormones such as cortisol, aldosterone, and sex steroids. StAR expression is particularly important in gonads and adrenal glands, where tropic hormones modulate production, and mutations can lead to severe endocrine disorders, including lipoid congenital adrenal hyperplasia. StAR protein shows predominant expression in ovary and testis, with immunoreactivity shifting from granulosa cells in early antral follicles to theca cell layers in mature follicles, highlighting a dynamic role in reproductive physiology. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using StAR Rabbit Monoclonal Antibody (EAB22820) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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