| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P | 35 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IGFBP2 Rabbit Monoclonal Antibody detects endogenous levels of IGFBP2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IGFBP2 is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). IGFBP2 plays a crucial role in regulating insulin-like growth factors (IGFs) by acting as a chaperone that escorts IGFs to target tissues, thereby influencing bioavailability and activity. IGFBP2 is predominantly expressed in several human tissues, including fetal eye and fetal brain, highlighting IGFBP2′s importance during development. IGFBP2′s ability to modulate IGF signaling is vital for various physiological processes, including growth and metabolism, and IGFBP2 dysregulation has been implicated in conditions such as cancer and metabolic disorders. IGFBP2′s interaction with IGFs not only affects distribution but also half-life, making IGFBP2 a key player in IGF signaling pathway. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, SH-SY5Y, Jurkat cells, using IGFBP2 Rabbit Monoclonal Antibody (EAB22268) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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