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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 75 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ARALAR/AGC1 Rabbit Polyclonal Antibody detects endogenous levels of ARALAR/AGC1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ARALAR also known as AGC1, SLC25A12 is a calcium-binding mitochondrial carrier protein. ARALAR plays a crucial role in calcium signaling within mitochondria, which is essential for the organelle′s response to various extracellular stimuli. ARALAR is primarily located in the inner mitochondrial membrane, where ARALAR facilitates the transport of aspartate and glutamate, thereby participating in the malate-aspartate NADH shuttle. ARALAR′s proper functioning is vital for synthesizing brain aspartate and N-acetylaspartate, both of which are important for neuronal health and myelin formation. Additionally, ARALAR′s ability to transmit small calcium signals to mitochondria through an increase in mitochondrial NADH is significant for maintaining cellular energy metabolism. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, Mouse liver cells, using ARALAR/AGC1 Rabbit Polyclonal Antibody (EAB11854) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry of paraffin-embedded Human prostate cancer tissue, using ARALAR/AGC1 Rabbit Polyclonal Antibody (EAB11854) at 1:100 dilution.
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