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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 56 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Septin-8 Rabbit Polyclonal Antibody detects endogenous levels of Septin-8 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Septin-8 is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septin-8 plays a crucial role in the organization of the cytoskeleton and is primarily located in the cytoplasm, where Septin-8 contributes to the formation of higher-order filamentous structures essential for cellular integrity and function. The localization of Septin-8 is particularly important as Septin-8 is involved in various cellular processes such as vesicle trafficking, apoptosis, and cytokinesis, which are vital for maintaining normal cellular activities and responses to stress. Additionally, Septin-8 interacts with other septins, including Septin-5 and cell division cycle related-1 (CDCrel-1), highlighting Septin-8′s role in complex protein networks that regulate cell division and signaling pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using Septin-8 Rabbit Polyclonal Antibody (EAB11856) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 56 kDa; Observed band size: 50 kDa |
