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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 113 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Sec24D Rabbit Polyclonal Antibody detects endogenous levels of Sec24D protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Sec24D is a member of the Sec24 subfamily of the Sec23/Sec24 family. Sec24D plays a crucial role in vesicle trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus, which is essential for proper secretion of proteins and lipids. Sec24D has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The COPII complex, with Sec24D as a vital component, functions as a coat that encapsulates ER-derived transport vesicles, facilitating transport of secretory proteins to the Golgi apparatus. Sec24D shares 50% amino acid identity with the ubiquitously expressed Sec24C protein, indicating a conserved function in protein transport and secretion across species. |
| Product Image Gallery | |
 Western blot analysis of extracts on A375, DU145, LO2 cells, using Sec24D Rabbit Polyclonal Antibody (EAB14364) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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