| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 12 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DYNLT1 Rabbit Polyclonal Antibody detects endogenous levels of DYNLT1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DYNLT1 also known as CW-1, TCTEL1, Tctex1 is a cytoplasmic dynein light chain. DYNLT1 plays a crucial role in the transport of cellular cargo along microtubules, which is essential for maintaining cellular organization and function. DYNLT1 is expressed in various human tissues, including the heart, placenta, skeletal muscle, kidney, pancreas, spleen, prostate, testis, ovary, ileum, and colon, highlighting its importance in diverse physiological processes. DYNLT1 interacts with other proteins such as Na+ CP type Xα (SCN10A) and is regulated by several key proteins, including dynactin, LIS1, and NudEL (NudE-like), which modulate dynein activity and ensure proper cellular transport mechanisms. The carboxy terminus of dynein, where DYNLT1 is located, is particularly important for microtubule-dependent motility and is highly conserved across species, underscoring the evolutionary significance of DYNLT1 in cellular dynamics. |
| Product Image Gallery | |
 Western blot analysis of extracts on SH-SY5Y cells, using DYNLT1 Rabbit Polyclonal Antibody (EAB14960) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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