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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 57 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TrxR2 Rabbit Polyclonal Antibody detects endogenous levels of TrxR2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TrxR2 also known as Thioredoxin reductase 2, TXNRD2 is a vital redox enzyme localized in mitochondria, where TrxR2 plays a crucial role in maintaining cellular redox balance and protecting against oxidative stress. TrxR2 is essential for cell viability as TrxR2 scavenges reactive oxygen species (ROS) within mitochondria and regulates mitochondrial apoptosis signaling pathway, thereby influencing cell survival and death. TrxR2 includes a conserved catalytic site critical for enzymatic function, allowing TrxR2 to reduce oxidized thioredoxin and other cellular components, which is important for various cellular processes, including DNA synthesis and transcription factor modulation. |
| Product Image Gallery | |
 Western blot analysis of extracts on HT29, Rat muscle cells, using TrxR2 Rabbit Polyclonal Antibody (EAB11862) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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