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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 85 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:100-500 FC=1:10-100 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CD71 Rabbit Monoclonal Antibody detects endogenous levels of CD71 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CD71 also known as Transferrin Receptor, TR, TFR, TFRC is a type II membrane glycoprotein forming a disulfide-linked homodimer of two identical subunits. CD71 maintains iron homeostasis by binding to transferrin, a serum iron-transport protein, and facilitates cellular iron uptake through receptor-mediated endocytosis. CD71 expression remains high in proliferating cells, reticulocytes, and erythroid precursors, while staying absent in resting leukocytes but becoming upregulated upon activation of lymphocytes, monocytes, and macrophages. CD71 appears on most dividing cells and brain endothelium, showing significance in hematopoiesis and neurobiology. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562 cells, using CD71 Rabbit Monoclonal Antibody (EAB22106) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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