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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 39 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TIM-1 Rabbit Polyclonal Antibody detects endogenous levels of TIM-1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TIM-1 also known as HAVCR1 is a single-pass type I membrane protein that plays a crucial role in the immune system, particularly in the development of T helper 2 (Th2) biased immune responses. TIM-1 is selectively expressed on Th2 cells, which are essential for mediating responses to extracellular pathogens and regulating allergic reactions. Expression of TIM-1 on the surface of these cells allows for the modulation of immune responses, making TIM-1 a significant player in conditions such as asthma and other allergic diseases. Additionally, TIM-1 serves as a receptor for the hepatitis A virus, highlighting TIM-1′s importance in viral pathogenesis. TIM-1 is widely expressed in various tissues, with the highest levels found in the testis and kidney, underscoring TIM-1′s potential roles in both immune regulation and organ-specific functions. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562 cells, using TIM-1 Rabbit Polyclonal Antibody (EAB14517) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 39 kDa; Observed band size: 40-50 kDa  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue, using TIM-1 Rabbit Polyclonal Antibody (EAB14517) at 1:100 dilution.
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