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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 41 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Wnt16 Rabbit Polyclonal Antibody detects endogenous levels of Wnt16 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Wnt16 is a member of the Wnt family of secreted glycoproteins, which are crucial for numerous developmental processes, including the regulation of cell growth and differentiation. Notably, Wnt-16 has two mRNA isoforms, Wnt16a and Wnt16b, which exhibit distinct expression patterns; Wnt16a is primarily found in the pancreas, while Wnt16b is abundantly expressed in adult kidney, placenta, brain, heart, and spleen, but not in bone marrow. The differential expression of these isoforms suggests a specialized role for Wnt16b in organ-specific functions and potential implications in developmental biology and disease. Wnt16 is implicated in the pathogenesis of certain leukemias, serving as a downstream target of the E2APbx1 hybrid gene, indicating that Wnt16 mediated autocrine signaling may play a role in the growth of preB acute lymphoblastoid leukemias. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat, Rat kidney cells, using Wnt16 Rabbit Polyclonal Antibody (EAB11815) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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