| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 61 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LRF/Pokemon Rabbit Polyclonal Antibody detects endogenous levels of LRF/Pokemon protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LRF is also known as Pokemon, ZBTB7A plays a crucial role in cell differentiation and is characterized by its unique structure, which includes a poxvirus zinc finger (POZ) domain at the N-terminus and Kruppel-type zinc fingers at the C-terminus. This structural configuration facilitates protein-protein interactions essential for LRF′s function as a transcription factor. LRF influences the transition from cellular proliferation to terminal differentiation, particularly during the differentiation of preadipocytes, thereby contributing to adipogenesis. Additionally, LRF can associate with active chromatin and enhance HIV-1 transcription by interacting with the long terminal repeat, highlighting LRF′s importance in both normal cellular processes and viral pathogenesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on PC12 cells, using LRF/Pokemon Rabbit Polyclonal Antibody (EAB11810) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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