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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB | 110 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PKD2 Rabbit Polyclonal Antibody detects endogenous levels of PKD2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PKD2 also known as Polycystin 2, PC2 is a member of the polycystin protein family. PKD2 plays a crucial role in calcium ion transport and cellular signaling. The localization of PKD2 at these cellular sites is significant, as PKD2 regulates calcium homeostasis and thus influences cell proliferation, differentiation, and survival. PKD2′s proper function is essential for kidney health, and mutations in the PKD2 gene are associated with autosomal dominant polycystic kidney disease (ADPKD), contributing to cyst formation in kidney tubules. PKD2 is known to interact with Polycystin-1, forming a complex that enhances AP-1 expression, which is critical for modulating gene expression linked to cell growth and apoptosis. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, MCF7, Mouse kidney cells, using PKD2 Rabbit Polyclonal Antibody (EAB14490) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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