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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 73 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | SDHA Rabbit Polyclonal Antibody detects endogenous levels of SDHA protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SDHA is a component of the succinate dehydrogenase complex which plays a crucial role in the mitochondrial respiratory chain, specifically in the conversion of succinate to fumarate, which is essential for aerobic respiration and energy production in cells. Mutations in SDHA can lead to severe mitochondrial dysfunction and are linked to various genetic disorders, including juvenile encephalopathy and Leigh Syndrome. SDHA is located within the inner mitochondrial membrane, where SDHA forms part of a larger enzyme complex that includes SDHB, SDHC, and SDHD subunits. This localization enables SDHA to effectively participate in the electron transport chain, facilitating electron transfer and contributing to ATP synthesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562, Jurkat, NIH/3T3, HepG2 cells, using SDHA Rabbit Polyclonal Antibody (EAB13023) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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