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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 88 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IFI16 Rabbit Polyclonal Antibody detects endogenous levels of IFI16 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IFI16 also known as IFNGIP1 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. IFI16 plays a significant role in immune response, particularly in viral DNA recognition, which is essential for initiating appropriate immune reactions. IFI16 is primarily localized in the nucleus, functioning as a transcriptional regulator and participating in gene expression modulation in response to interferon signaling. Nuclear localization of IFI16 enables interaction with various transcription factors and chromatin, influencing expression of genes critical for immune defense. IFI16 forms complexes with other proteins, such as myeloid cell nuclear differentiation antigen (MNDA), further highlighting IFI16′s importance in immune response regulation. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using IFI16 Rabbit Polyclonal Antibody (EAB13044) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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