| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 12 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Thioredoxin 1/TRX1 Rabbit Polyclonal Antibody detects endogenous levels of Thioredoxin 1/TRX1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TRX1(Thioredoxin 1) also known as TXN is a crucial redox protein that plays a significant role in cellular processes by maintaining the redox balance within cells. TRX1 is primarily located in the cytoplasm but can also be found in the nucleus and mitochondria, highlighting versatility in cellular functions. TRX1 presence in these locations is vital for protecting cells from oxidative stress, as TRX1 helps to reduce disulfide bonds in proteins, thereby maintaining their functional state. Additionally, TRX1 is involved in regulating various signaling pathways and transcription factors, which are essential for cell growth and survival. TRX1 interaction with other proteins, such as Thioredoxin Reductase (TrxR), further emphasizes importance in cellular redox homeostasis and potential implications in diseases, including cancer, where TRX1 overexpression can contribute to tumor progression and resistance to therapy. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse liver cells, using Thioredoxin 1/TRX1 Rabbit Polyclonal Antibody (EAB13062) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human skin tissue, using Thioredoxin 1 Rabbit Polyclonal Antibody (EAB13062) at 1:200 dilution.
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