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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 113 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-ULK1 (Ser757) Rabbit Polyclonal Antibody detects endogenous levels of ULK1 protein only when phosphorylated at Ser757. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ULK1 plays a crucial role in initiating autophagy, a vital cellular process that degrades and recycles cellular components, maintaining cellular homeostasis and responding to stress conditions. This function is particularly important in various diseases, including cancer and neurodegenerative disorders, where autophagy can influence cell survival and death. ULK1 forms a complex with ULK2, and both proteins share significant homology with UNC-51 kinase from Caenorhabditis elegans and APG1 kinase in yeast, which are also involved in autophagy regulation. Mapping to human chromosome 12q24.3, ULK1 is ubiquitously expressed across tissues, highlighting its fundamental role in cellular processes. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293 cells, using Phospho-ULK1 (Ser757) Rabbit Polyclonal Antibody (EAB10843) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Predicted band size: 113 kDa; Observed band size: 113-150 kDa |
