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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 39 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IRF-2 Rabbit Polyclonal Antibody detects endogenous levels of IRF-2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IRF-2(Interferon regulatory factor 2) is a member of the interferon regulatory transcription factor (IRF) family. IRF-2 plays a crucial role in the regulation of immune responses by acting as a transcriptional repressor of interferon regulatory factor-1, thereby modulating the expression of type I interferons and interferon-inducible genes. This regulatory function is vital for maintaining the balance between immune activation and suppression, which is essential for preventing excessive inflammation and autoimmunity. IRF-2 is primarily located in the nucleus, where IRF-2 binds to specific DNA sequences in the promoters of target genes, influencing their transcriptional activity. Understanding the cellular localization of IRF-2 highlights IRF-2′s role in gene regulation and potential impact on cellular responses to viral infections and other immune challenges. |
| Product Image Gallery | |
 Western blot analysis of extracts on COLO205, Jurkat cells, using IRF-2 Rabbit Polyclonal Antibody (EAB13115) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 39 kDa; Observed band size: 47 kDa  Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue, using IRF-2 Rabbit Polyclonal Antibody (EAB13115) at 1:100 dilution. |
