www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 60 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | GATA-6 Rabbit Polyclonal Antibody detects endogenous levels of GATA-6 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
GATA-6 is a member of the GATA family of transcription factors, characterized by a conserved zinc finger DNA-binding domain that binds to specific DNA sequences, particularly the WGATAR consensus sequence. GATA-6 plays a crucial role in gene expression regulation during development, particularly in heart, pancreas, and reproductive tissues. GATA-6 is essential for proper differentiation and function of various cell types, including cardiac myocytes and endocrine cells. GATA-6 expression is tightly regulated and interacts with other GATA family members, such as GATA-4 and GATA-5, to coordinate complex gene regulatory networks. Understanding GATA-6 interactions and regulatory mechanisms is vital, as dysregulation has been implicated in various developmental disorders and diseases, including congenital heart defects and certain cancers. GATA-6′s ability to form heterodimers with other GATA factors enhances regulatory capabilities, making GATA-6 a key player in transcriptional control of genes critical for cellular identity and function. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 293 cells, using GATA-6 Rabbit Polyclonal Antibody (EAB13155) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 60 kDa; Observed band size: 45 kDa |
