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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 270 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Talin-1 Rabbit Polyclonal Antibody detects endogenous levels of Talin-1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Talin-1 also known as TLN1 is a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. Talin-1 plays a crucial role in cell adhesion and signaling by linking integrins to the actin cytoskeleton, which is essential for maintaining cell shape and facilitating communication between the extracellular matrix and the cell interior. This interaction is vital for processes such as cell migration, proliferation, and differentiation, making Talin-1 a key player in tissue development and repair. Additionally, Talin-1 undergoes post-translational modifications, including phosphorylation, which can influence activity and interactions with other proteins. These modifications regulate the assembly and disassembly of focal adhesions, thereby impacting cellular responses to mechanical and biochemical signals. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using Talin-1 Rabbit Polyclonal Antibody (EAB13156) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human kidney tissue, using Talin-1 Rabbit Polyclonal Antibody (EAB13156) at 1:100 dilution.
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