| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 71 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CD2AP Rabbit Polyclonal Antibody detects endogenous levels of CD2AP protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CD2AP(CD2 associated protein) is a scaffolding molecule that regulates the actin cytoskeleton. CD2AP plays a crucial role as a cytosolic adaptor molecule that interacts with the intracellular portion of CD2 during T cell activation, facilitating cell adhesion through CD2-mediated binding to ligands on antigen-presenting cells. This interaction enhances antigen-specific T cell activation, promotes cell clustering, and induces cytoskeletal polarization, which are essential processes in the immune response. CD2AP is predominantly expressed in the liver, thymus, and spleen, and CD2AP structure includes three Src Homology 3 (SH3) domains that are critical for binding to CD2. |
| Product Image Gallery | |
 Western blot analysis of extracts on COLO205, Mouse testis cells, using CD2AP Rabbit Polyclonal Antibody (EAB13163) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
