| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF, ELISA | 219 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Dicer Rabbit Polyclonal Antibody detects endogenous levels of Dicer protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Dicer is a crucial component of the RNA interference pathway, playing a vital role in the processing of small RNA molecules that regulate gene expression. Dicer is primarily located in the cytoplasm of mammalian cells, where Dicer co-localizes with calreticulin in the endoplasmic reticulum, highlighting Dicer′s importance in cellular RNA metabolism. Dicer′s localization allows for efficient processing of precursor microRNAs and short hairpin RNAs into functional small interfering RNAs, which are essential for targeted degradation of homologous mRNAs. Dicer′s ability to cleave RNA precursors into 21-23 base pair double-stranded RNAs is critical for gene expression regulation and maintaining cellular homeostasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7, A431, CACO2 cells, using Dicer Rabbit Polyclonal Antibody (EAB10779) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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