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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 25 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-CD79A (Tyr182) Rabbit Polyclonal Antibody detects endogenous levels of CD79A protein only when phosphorylated at Tyr182. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CD79A also known as MB-1, IGalpha is a crucial component of the B cell antigen receptor complex, which plays a vital role in B cell activation and immune response. CD79A protein is located on the surface of B cells, where CD79A forms a heterodimer with CD79B, facilitating association with membrane immunoglobulins such as IgM and IgD. This interaction is essential for effective surface expression of these immunoglobulins, enabling B cells to present antigens and initiate immune responses. Additionally, cytoplasmic tails of CD79A and CD79B contain immuno-receptor tyrosine-based activation motifs (ITAMs) that are critical for triggering downstream signaling pathways upon antigen binding, ultimately leading to B cell activation and proliferation. |
| Product Image Gallery | |
 Western blot analysis of extracts on KB cells, using Phospho-CD79A (Tyr182) Rabbit Polyclonal Antibody (EAB13343) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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