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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 34 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Sox2 (Ser250/Ser251) Rabbit Polyclonal Antibody detects endogenous levels of Sox2 protein when dually or singly phosphorylated at Ser250 and Ser251. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Sox2 also known as lcc, ysb is a member of the SRY-related HMG-box (SOX) family of transcription factors. Sox2 plays a crucial role in maintaining pluripotency and self-renewal of embryonic stem cells, thereby governing cell fate decisions and orchestrating key developmental processes. Sox2′s nuclear localization is essential for regulating gene expression, influencing pathways fundamental to embryonic development and maintenance of stem cell populations. Dysregulation of Sox2 has been implicated in various developmental disorders and diseases, including certain cancers, underscoring Sox2′s significance in both normal physiology and pathological conditions. |
| Product Image Gallery | |
 Western blot analysis of extracts on SH-SY5Y cells, using Phospho-Sox2 (Ser250/Ser251) Rabbit Polyclonal Antibody (EAB13327) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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