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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 149 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Raptor Rabbit Polyclonal Antibody detects endogenous levels of Raptor protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Raptor also known as RPTOR is a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. Raptor plays a pivotal role in the mammalian target of rapamycin (mTOR) signaling pathway, which is crucial for regulating cell growth, proliferation, and survival in response to nutrient availability. Specifically, Raptor acts as a scaffold that facilitates interaction between mTOR and substrates, including 4E-BP1, thereby promoting phosphorylation and activation. This interaction is vital for cellular response to nutrient levels, as Raptor-mTOR complex is sensitive to changes in nutrient status, allowing cells to adapt growth and metabolism accordingly. Under nutrient-rich conditions, Raptor enhances mTOR activity, while in nutrient-deprived states, Raptor serves as a negative regulator, inhibiting mTOR signaling to conserve resources. |
| Product Image Gallery | |
 Western blot analysis of extracts on HCT116 cells, using Raptor Rabbit Polyclonal Antibody (EAB13368) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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