www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 60 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RanBP3 Rabbit Polyclonal Antibody detects endogenous levels of RanBP3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RanBP3 is a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. RanBP3 plays a crucial role as a scaffold protein that facilitates the assembly of export complexes, particularly by promoting the binding of Crm1 to RCC1 in the presence of Ran GTP. This interaction is vital for the export of proteins and RNA from the nucleus, a process essential for maintaining cellular function and regulating gene expression. Additionally, Ran BP-3′s ability to bind β-catenin highlights involvement in the inhibition of the Wnt signaling pathway, which is important for various developmental processes and cellular functions. The precise regulation of these interactions underscores the significance of Ran BP-3 in cellular transport mechanisms and potential implications in cancer biology and other diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on A549 cells, using RanBP3 Rabbit Polyclonal Antibody (EAB13370) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
