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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 21 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rac2 Rabbit Polyclonal Antibody detects endogenous levels of Rac2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rac2 is a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. Rac2 plays a crucial role in regulating various cellular processes, particularly in myeloid cells where Rac2 is predominantly expressed. Rac2 is essential for the proper functioning of the NADPH oxidase complex in neutrophils, which is responsible for generating reactive oxygen species that are vital for the immune response against pathogens. Rac2′s ability to interact with other proteins, such as GTPase-activating proteins (GAPs), is significant as these interactions modulate Rac2 activity by accelerating GTP hydrolysis, thus influencing signaling pathways. Given specific expression in myeloid cells and role in immune responses, Rac 2 serves as an important target for research into immune function and related disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on U2OS cells, using Rac2 Rabbit Polyclonal Antibody (EAB13284) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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