| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 98 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PSD93 Rabbit Polyclonal Antibody detects endogenous levels of PSD93 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PSD93 also known as DLG2 is a member of the membrane-associated guanylate kinase (MAGUK) family. PSD93 plays a crucial role in assembling signal transduction complexes at synaptic sites, particularly in hippocampal neurons where PSD93 is exclusively localized to postsynaptic sites. PSD93 is essential for clustering and anchoring NMDA receptors at the synapse, which is vital for synaptic plasticity and memory formation. Notably, PSD93 interacts specifically with glutamate receptor subunit delta2, which is enriched in Purkinje neuron cell bodies and dendrites, facilitating delta2 clustering when coexpressed and ensuring their co-localization at parallel fiber synapses. PSD93′s ability to mediate these interactions underscores its importance in synaptic function and neuronal communication, making PSD93 a valuable target for research in neurobiology and related fields. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 293T, HepG2 cells, using PSD93 Rabbit Polyclonal Antibody (EAB13387) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistryt analysis of paraffin-embedded Human brain tissue, using PSD93 Rabbit Polyclonal Antibody (EAB13387) at 1:100 dilution.
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