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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 105 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | NMDAR1 Rabbit Monoclonal Antibody detects endogenous levels of NMDAR1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NMDAR1 also known as NMDAζ1, GRIN1 plays a crucial role in mediating excitatory neurotransmission in the brain, which is essential for processes such as learning, memory, and synaptic plasticity. NMDAR1 is primarily located in the postsynaptic membrane of neurons, where NMDAR1 forms part of the NMDA receptor complex, allowing for calcium ion influx in response to glutamate binding. The unique structure of NMDA receptors, which includes a high permeability to calcium ions, is vital for their function in synaptic signaling and plasticity, as calcium influx activates various intracellular signaling pathways that influence neuronal function and survival. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse brain, Rat brain cells, using NMDAR1 Rabbit Monoclonal Antibody (EAB22314) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 105 kDa; Observed band size: 120 kDa |
