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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 23 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-LIN28A (Ser200) Rabbit Polyclonal Antibody detects endogenous levels of LIN28A only when phosphorylated at Ser200. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LIN28A is a LIN28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. LIN28A is a highly conserved, RNA-binding protein located primarily in the cytoplasm, playing a crucial role in regulating developmental timing during embryogenesis. LIN28A presence is particularly significant in embryos, embryonic stem cells, and embryonal carcinoma cells, where LIN28A influences cellular differentiation and growth. LIN28A interacts with insulin-like growth factor II (IGF-II), enhancing protein synthesis efficiency in differentiating myoblasts, which is vital for muscle development and regeneration. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using Phospho-LIN28A (Ser200) Rabbit Polyclonal Antibody (EAB14441) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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