| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 128 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF =1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Abl2 Rabbit Polyclonal Antibody detects endogenous levels of Abl2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Abl2 also known as ARG is a member of the Abelson family of nonreceptor tyrosine protein kinases. Abl2 plays a crucial role in cellular signaling pathways, particularly in regulating cell growth and differentiation. Abl2 contains both SH2 and SH3 domains, which are essential for protein-protein interactions, allowing engagement with various signaling molecules. One significant interaction is with c-Crk, a protein involved in regulating cytoskeletal dynamics and cell migration. Phosphorylation of c-Crk by Arg is vital for modulating these processes, which are important in development and immune responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on AD293 cells, using Abl2 Rabbit Polyclonal Antibody (EAB13466) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Mouse brain tissue, using Abl2 Rabbit Polyclonal Antibody (EAB13466) at 1:100 dilution.
 Immunohistochemical analysis of paraffin-embedded Rat brain tissue, using Abl2 Rabbit Polyclonal Antibody (EAB13466) at 1:100 dilution.
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