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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 79 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TBX3 Rabbit Polyclonal Antibody detects endogenous levels of TBX3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. TBX3 plays a crucial role in developmental processes, particularly in the regulation of gene expression during embryonic development. TBX3 functions as a transcriptional repressor, which is essential for maintaining the balance of gene expression necessary for proper cellular differentiation and organogenesis. Dysregulation of TBX3 has been implicated in various human diseases, including ulnar-mammary syndrome and certain types of cancer, highlighting TBX3′s importance in both developmental biology and pathology. The T-box transcription factor family, to which TBX3 belongs, is characterized by a conserved DNA-binding domain that allows specific gene promoter interactions, thereby influencing the transcriptional landscape of developing tissues. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, Mouse kidney, Mouse brain cells, using TBX3 Rabbit Polyclonal Antibody (EAB13478) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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