| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 42 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PSMD11 Rabbit Polyclonal Antibody detects endogenous levels of PSMD11 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PSMD11 also known as S9, Rpn6 is a crucial regulatory subunit of the 26S proteasome, a complex responsible for the selective degradation of ubiquitinated proteins, which is vital for maintaining cellular homeostasis and regulating various cellular processes. PSMD11 consists of 422 amino acids and features a PCI domain, which is essential for its role in the ATP-dependent degradation pathway. Proper functioning of PSMD11 ensures that damaged or misfolded proteins are efficiently removed from the cell, preventing potential toxic accumulation that could lead to cellular dysfunction or disease. The gene encoding PSMD11 is located on human chromosome 17, a region that encompasses over 2.5% of the human genome and is known to encode more than 1,200 genes, highlighting PSMD11′s importance in cellular regulation and proteostasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293, HepG2, Raw264.7 cells, using PSMD11 Rabbit Polyclonal Antibody (EAB13523) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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