| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 62 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | EAAT2 Rabbit Polyclonal Antibody detects endogenous levels of EAAT2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
EAAT2(Excitatory amino acid transporter 2) also known as GLT-1, SLC1A2 is a member of a family of solute transporter proteins. EAAT2 plays a crucial role in the central nervous system by mediating the uptake of the excitatory neurotransmitter L-glutamate, which is vital for maintaining synaptic homeostasis and preventing excitotoxicity. EAAT2 protein is predominantly localized in astrocytes and is essential for clearing excess glutamate from the synaptic cleft following neurotransmission, thereby protecting neurons from potential damage caused by glutamate accumulation. Proper functioning of EAAT2 is critical for normal brain function, as dysregulation of glutamate transport can lead to various neurological disorders, including epilepsy, neurodegenerative diseases, and mood disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse brain, Rat brain cells, using EAAT2 Rabbit Polyclonal Antibody (EAB13512) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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