| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 57 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | EAAT3 Rabbit Polyclonal Antibody detects endogenous levels of EAAT3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
EAAT3 also known as SLC1A1 is a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. EAAT3 activity contributes to neurotransmitter clearance, synaptic signaling homeostasis, and neuronal vulnerability to oxidative stress through glutamate-dependent pathways that intersect with cysteine uptake and glutathione synthesis. In human tissues, EAAT3 is linked to neuronal and epithelial transport processes and has been studied in the context of altered excitatory neurotransmission and cellular stress responses. Genetic and expression changes in EAAT3 have been associated with neuropsychiatric and neurodevelopmental phenotypes, motivating mechanistic studies of transporter regulation and downstream signaling. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293, Jurkat cells, using EAAT3 Rabbit Polyclonal Antibody (EAB13513) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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