| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 38 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Annexin A2 Rabbit Polyclonal Antibody detects endogenous levels of Annexin A2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Annexin A2 also known as Annexin II, Annexin-2, ANXA2 is a member of the annexin family. Annexin A2 plays a crucial role in various cellular processes. Predominantly located in the cytoplasm and on the cell surface, Annexin A2 mediates membrane-related events like endocytosis, exocytosis, and cellular adhesion. Surface-expressed Annexin A2 acts as a receptor for plasminogen and tissue plasminogen activator (tPA), facilitating plasmin generation and playing a key role in fibrinolysis and blood coagulation. Annexin A2 can exist as a monomer or form a heterotetramer complex with S100A10 (p11), known as calpactin I, which is involved in signal transduction pathways. Annexin A2 is also a substrate for protein kinase C (PKC) and Src family kinases, indicating involvement in phosphorylation-dependent signaling mechanisms. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, NIH/3T3 cells, using Annexin A2 Rabbit Polyclonal Antibody (EAB13580) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human brain tissue, using Annexin A2 Rabbit Polyclonal Antibody (EAB13580) at 1:100 dilution.
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