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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, FC | 21 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 FC=1:10-100 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HP1γ Rabbit Monoclonal Antibody detects endogenous levels of HP1γ protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HP1γ also known as HP1gamma, CBX3 is a member of the heterochromatin protein family, plays a crucial role in the regulation of gene expression and the maintenance of chromatin structure. HP1γ is primarily located in the nucleus, where HP1γ binds to heterochromatin and is essential for the formation and stability of this tightly packed chromatin. HP1γ presence in heterochromatin is vital for the repression of transcription and the protection of genomic integrity, as HP1γ helps to prevent unwanted recombination and transcriptional activity in these regions. Additionally, HP1γ interacts with various proteins, including chromatin remodeling complexes and histone methyltransferases, which further underscores HP1γ importance in chromatin dynamics and epigenetic regulation. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, NIH/3T3, Mouse spleen cells, using HP1γ Rabbit Monoclonal Antibody (EAB21244) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 21 kDa; Observed band size: 24 kDa |
