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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 100 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-NFAT1/NFATc2 (Ser326) Rabbit Polyclonal Antibody detects endogenous levels of NFAT1/NFATc2 protein only when phosphorylated at Ser326. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NFAT1also known as NFATc2 is a member of the nuclear factor of activated T cells (NFAT) family. NFAT1 plays a crucial role in the immune response by regulating the expression of cytokine genes in T cells. Upon activation of the T cell receptor, the calcium-dependent protein phosphatase calcineurin is stimulated, leading to the translocation of NFAT1 from the cytoplasm to the nucleus. In the nucleus, NFAT1 collaborates with AP-1 transcription factors to initiate the transcription of genes essential for T cell activation and function. This process is vital for the proper immune response, as NFAT1 influences the production of cytokines that mediate inflammation and immune regulation. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7 cells treated with LPS, using Phospho-NFAT1/NFATc2 (Ser326) Rabbit Polyclonal Antibody (EAB13533) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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