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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 64 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TRAF3 Rabbit Polyclonal Antibody detects endogenous levels of TRAF3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TRAF3 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF3 plays a crucial role in the regulation of immune responses and cell signaling pathways, particularly in the context of tumor necrosis factor (TNF) receptor-mediated signaling. TRAF3 is primarily involved in the formation of signaling complexes that modulate the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and mitogen-activated protein kinase (MAPK) pathways, which are essential for the immune response and inflammation. Proper functioning of TRAF3 is vital, as dysregulation can lead to various diseases, including autoimmune disorders and cancer. TRAF3 interacts with other proteins in the TNF receptor superfamily, such as TRAF1 and TRAF2, to form heterodimeric complexes that enhance signaling efficiency. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562, Jurkat cells, using TRAF3 Rabbit Polyclonal Antibody (EAB11599) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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