| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 37 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | AKR1C3/DD3 Rabbit Polyclonal Antibody detects endogenous levels of AKR1C3/DD3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
AKR1C3 also known as DD3 is a member of the aldo/keto reductase superfamily and plays a crucial role in steroid and xenobiotic metabolism. DD3 recognizes an enzyme that catalyzes the reduction of 3-keto-5-dihydrosteroids, essential for regulating steroid hormone levels in the body. DD3 maintains hormonal balance and influences various physiological processes, including reproduction and metabolism. Among its isoforms, DD3 uniquely catalyzes the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol, highlighting specialized function in detoxifying environmental pollutants.
|
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, COLO205 cells, using AKR1C3/DD3 Rabbit Polyclonal Antibody (EAB13630) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
